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تاریخ:جمعه 31 تیر 1390-12:38 ب.ظ

نویسنده :سعید عفیفی

استامینوفن از جمله داروهای ایجاد کننده سمیت کبدی

این رزیدنت داروسازی تصریح کرد: استامینوفن به عنوان یکی از داروهای شایع که از دز بالا می تواند سمیت کبدی ایجاد نماید و به دلیل در دسترس بودن احتیاج به ملاحظات ویژه ای دارد.

وی گفت: نکته تاسف آور در مسمومیت با استامینوفن این است که در 24 ساعت اول بیمار علایم آزمایشگاهی و بالینی خاص سمیت کبدی را بروز نداده و حداکثر علایم غیراختصاصی مانند تهوع را ذکر می کند که در تشخیص چندان کمک کنده نمی باشد.

دكتر ارفع بیان داشت: سمیت کبدی اصلی بیمار بعد از حدود 48 ساعت رخ می دهد و گاهی این سمیت کبدی می تواند آن قدر پیشرونده باشد که تنها راه نجات بیمار پیوند کبد باشد.

وی در پایان خاطرنشان کرد: مسمومیت شدید و پیشرونده در استفاده از استامینوفن در صورتی که با اقدامات درمانی مناسب همراه نباشد می تواند طی 3 تا 5 روز مرگ بیمار را در پی داشته باشد.


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